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Receptor-Mediated Endocytosis and Brain Delivery of Therapeutic Biologics
Transport of macromolecules across the blood-brain-barrier (BBB) requires both specific and nonspecific interactions between macromolecules and proteins/receptors expressed on the luminal and/or the abluminal surfaces of the brain capillary endothelial cells. Endocytosis and transcytosis play import...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693099/ https://www.ncbi.nlm.nih.gov/pubmed/23840214 http://dx.doi.org/10.1155/2013/703545 |