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Stress-induced anhedonia is associated with hypertrophy of medium spiny neurons of the nucleus accumbens

There is accumulating evidence that the nucleus accumbens (NAc) has an important role in the pathophysiology of depression. As the NAc is a key component in the neural circuitry of reward, it has been hypothesized that anhedonia, a core symptom of depression, might be related to dysfunction of this...

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Detalles Bibliográficos
Autores principales: Bessa, J M, Morais, M, Marques, F, Pinto, L, Palha, J A, Almeida, O F X, Sousa, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693402/
https://www.ncbi.nlm.nih.gov/pubmed/23736119
http://dx.doi.org/10.1038/tp.2013.39