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mRNA and protein expression for novel GABA(A) receptors θ and ρ2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway

Fragile X mental retardation protein (FMRP) is an RNA-binding protein that targets ∼5% of all mRNAs expressed in the brain. Previous work by our laboratory demonstrated significantly lower protein levels for FMRP in lateral cerebella of subjects with schizophrenia, bipolar disorder and major depress...

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Detalles Bibliográficos
Autores principales: Fatemi, S H, Folsom, T D, Rooney, R J, Thuras, P D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693405/
https://www.ncbi.nlm.nih.gov/pubmed/23778581
http://dx.doi.org/10.1038/tp.2013.46