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mRNA and protein expression for novel GABA(A) receptors θ and ρ2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway
Fragile X mental retardation protein (FMRP) is an RNA-binding protein that targets ∼5% of all mRNAs expressed in the brain. Previous work by our laboratory demonstrated significantly lower protein levels for FMRP in lateral cerebella of subjects with schizophrenia, bipolar disorder and major depress...
Autores principales: | Fatemi, S H, Folsom, T D, Rooney, R J, Thuras, P D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693405/ https://www.ncbi.nlm.nih.gov/pubmed/23778581 http://dx.doi.org/10.1038/tp.2013.46 |
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