Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay

OBJECTIVES: Lead antituberculosis (anti-TB) molecules with novel mechanisms of action are urgently required to fuel the anti-TB drug discovery pipeline. The aim of this study was to validate the use of the high-throughput spot culture growth inhibition (HT-SPOTi) assay for screening libraries of com...

Descripción completa

Detalles Bibliográficos
Autores principales: Guzman, Juan D, Evangelopoulos, Dimitrios, Gupta, Antima, Birchall, Kristian, Mwaigwisya, Solomon, Saxty, Barbara, McHugh, Timothy D, Gibbons, Simon, Malkinson, John, Bhakta, Sanjib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2013
Materias:
Global Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693423/
https://www.ncbi.nlm.nih.gov/pubmed/23794563
http://dx.doi.org/10.1136/bmjopen-2013-002672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693423/
https://www.ncbi.nlm.nih.gov/pubmed/23794563
http://dx.doi.org/10.1136/bmjopen-2013-002672

Ejemplares similares