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Drug-resistant colon cancer cells produce high carcinoembryonic antigen and might not be cancer-initiating cells

PURPOSE: We evaluated the higher levels of carcinoembryonic antigen (CEA) secreted by the LoVo human colon carcinoma cells in a medium containing anticancer drugs. Drug-resistant LoVo cells were analyzed by subcutaneously xenotransplanting them into mice. The aim of this study was to evaluate whethe...

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Detalles Bibliográficos
Autores principales: Lee, Hsin-chung, Ling, Qing-Dong, Yu, Wan-Chun, Hung, Chunh-Ming, Kao, Ta-Chun, Huang, Yi-Wei, Higuchi, Akon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693723/
https://www.ncbi.nlm.nih.gov/pubmed/23818760
http://dx.doi.org/10.2147/DDDT.S45890