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SeqSIMLA: a sequence and phenotype simulation tool for complex disease studies

BACKGROUND: Association studies based on next-generation sequencing (NGS) technology have become popular, and statistical association tests for NGS data have been developed rapidly. A flexible tool for simulating sequence data in either unrelated case–control or family samples with different disease...

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Detalles Bibliográficos
Autores principales: Chung, Ren-Hua, Shih, Chung-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693898/
https://www.ncbi.nlm.nih.gov/pubmed/23782512
http://dx.doi.org/10.1186/1471-2105-14-199