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Amyloid-β peptide-induced extracellular S100A9 depletion is associated with decrease of antimicrobial peptide activity in human THP-1 monocytes

BACKGROUND: S100A9 protein (myeloid-related protein MRP14, also referred to as calgranulin B) is a reliable marker of inflammation, an important proinflammatory factor of innate immunity and acts as an additional antimicrobial peptide in the innate immune system. Evidence indicates that S100A9 contr...

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Detalles Bibliográficos
Autores principales: Lee, Eun Ok, Yang, Ji Hye, Chang, Keun-A, Suh, Yoo-Hun, Chong, Young Hae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693929/
https://www.ncbi.nlm.nih.gov/pubmed/23721320
http://dx.doi.org/10.1186/1742-2094-10-68