Measurement of Cancer Cell Growth Heterogeneity through Lentiviral Barcoding Identifies Clonal Dominance as a Characteristic of In Vivo Tumor Engraftment

Advances in the fields of cancer initiating cells and high-throughput in vivo shRNA screens have highlighted a need to observe the growth of tumor cells in cancer models at the clonal level. While in vivo cancer cell growth heterogeneity in xenografts has been described, it has yet to be measured. H...

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Detalles Bibliográficos
Autores principales: Nolan-Stevaux, Olivier, Tedesco, Donato, Ragan, Seamus, Makhanov, Mikhail, Chenchik, Alex, Ruefli-Brasse, Astrid, Quon, Kim, Kassner, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693957/
https://www.ncbi.nlm.nih.gov/pubmed/23840661
http://dx.doi.org/10.1371/journal.pone.0067316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693957/
https://www.ncbi.nlm.nih.gov/pubmed/23840661
http://dx.doi.org/10.1371/journal.pone.0067316

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