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Targeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective Immunity

Efficient vaccination against the parasite Leishmania major, the causative agent of human cutaneous leishmaniasis, requires development of type 1 T-helper (Th1) CD4(+) T cell immunity. Because of their unique capacity to initiate and modulate immune responses, dendritic cells (DCs) are attractive ta...

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Detalles Bibliográficos
Autores principales: Matos, Ines, Mizenina, Olga, Lubkin, Ashira, Steinman, Ralph M., Idoyaga, Juliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694010/
https://www.ncbi.nlm.nih.gov/pubmed/23840706
http://dx.doi.org/10.1371/journal.pone.0067453