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Targeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective Immunity
Efficient vaccination against the parasite Leishmania major, the causative agent of human cutaneous leishmaniasis, requires development of type 1 T-helper (Th1) CD4(+) T cell immunity. Because of their unique capacity to initiate and modulate immune responses, dendritic cells (DCs) are attractive ta...
Autores principales: | Matos, Ines, Mizenina, Olga, Lubkin, Ashira, Steinman, Ralph M., Idoyaga, Juliana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694010/ https://www.ncbi.nlm.nih.gov/pubmed/23840706 http://dx.doi.org/10.1371/journal.pone.0067453 |
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