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Phenotype, donor age and gender affect function of human bone marrow-derived mesenchymal stromal cells

BACKGROUND: Mesenchymal stromal cells (MSCs) are attractive for cell-based therapies ranging from regenerative medicine and tissue engineering to immunomodulation. However, clinical efficacy is variable and it is unclear how the phenotypes defining bone marrow (BM)-derived MSCs as well as donor char...

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Detalles Bibliográficos
Autores principales: Siegel, Georg, Kluba, Torsten, Hermanutz-Klein, Ursula, Bieback, Karen, Northoff, Hinnak, Schäfer, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694028/
https://www.ncbi.nlm.nih.gov/pubmed/23758701
http://dx.doi.org/10.1186/1741-7015-11-146