Cargando…

Phenotype, donor age and gender affect function of human bone marrow-derived mesenchymal stromal cells

BACKGROUND: Mesenchymal stromal cells (MSCs) are attractive for cell-based therapies ranging from regenerative medicine and tissue engineering to immunomodulation. However, clinical efficacy is variable and it is unclear how the phenotypes defining bone marrow (BM)-derived MSCs as well as donor char...

Descripción completa

Detalles Bibliográficos
Autores principales:	Siegel, Georg, Kluba, Torsten, Hermanutz-Klein, Ursula, Bieback, Karen, Northoff, Hinnak, Schäfer, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694028/ https://www.ncbi.nlm.nih.gov/pubmed/23758701 http://dx.doi.org/10.1186/1741-7015-11-146

Ejemplares similares

Functional investigations on human mesenchymal stem cells exposed to magnetic fields and labeled with clinically approved iron nanoparticles
por: Schäfer, Richard, et al.
Publicado: (2010)

Comparing the Immunomodulatory Properties of Bone Marrow, Adipose Tissue, and Birth-Associated Tissue Mesenchymal Stromal Cells
por: Mattar, Philipp, et al.
Publicado: (2015)

Recent advances in understanding mesenchymal stromal cells
por: Rendra, Erika, et al.
Publicado: (2020)

Translating Research into Clinical Scale Manufacturing of Mesenchymal Stromal Cells
por: Bieback, Karen, et al.
Publicado: (2011)

Where is the common ground between bone marrow mesenchymal stem/stromal cells from different donors and species?
por: Jones, Elena, et al.
Publicado: (2015)

Editorial: Current Progress in Mesenchymal Stem/Stromal Cell Research
por: da Silva Meirelles, Lindolfo, et al.
Publicado: (2021)

Compression Bioreactor-Based Mechanical Loading Induces Mobilization of Human Bone Marrow-Derived Mesenchymal Stromal Cells into Collagen Scaffolds In Vitro
por: Gamez, Carolina, et al.
Publicado: (2020)

Functional and differential proteomic analyses to identify platelet derived factors affecting ex vivo expansion of mesenchymal stromal cells
por: Kinzebach, Sven, et al.
Publicado: (2013)

Harmonised culture procedures minimise but do not eliminate mesenchymal stromal cell donor and tissue variability in a decentralised multicentre manufacturing approach
por: Calcat-i-Cervera, Sandra, et al.
Publicado: (2023)

Evaluation of phenotypic, functional and molecular characteristics of porcine mesenchymal stromal/stem cells depending on donor age, gender and tissue source
por: OCK, Sun-A, et al.
Publicado: (2016)

The Metastatic Bone Marrow Niche in Neuroblastoma: Altered Phenotype and Function of Mesenchymal Stromal Cells
por: Hochheuser, Caroline, et al.
Publicado: (2020)

Pooled human bone marrow-derived mesenchymal stromal cells with defined trophic factors cargo promote dermal wound healing in diabetic rats by improved vascularization and dynamic recruitment of M2-like macrophages
por: Willer, Hélène, et al.
Publicado: (2022)

Effect of the extracellular component of bone marrow mesenchymal stromal cells from healthy donors on hematologic neoplasms and their angiogenesis
por: Gladkova, Nina, et al.
Publicado: (2020)

Mesenchymal Stromal Cell Secretome Is Affected by Tissue Source and Donor Age
por: Turlo, Agnieszka J, et al.
Publicado: (2023)

Laminin-5 and type I collagen promote adhesion and osteogenic differentiation of animal serum-free expanded human mesenchymal stromal cells
por: Mittag, Falk, et al.
Publicado: (2012)

Modulating endothelial adhesion and migration impacts stem cell therapies efficacy
por: Schäfer, Richard, et al.
Publicado: (2020)

Molecular signature of human bone marrow-derived mesenchymal stromal cell subsets
por: Kuçi, Selim, et al.
Publicado: (2019)

Femur bone marrow from brain death deceased donors as source of human mesenchymal stromal cells for cell therapy
por: Echarte, Lourdes, et al.
Publicado: (2023)

Human Adipose Tissue-Derived Mesenchymal Stromal Cells Inhibit CD4+ T Cell Proliferation and Induce Regulatory T Cells as Well as CD127 Expression on CD4+CD25+ T Cells
por: Fiori, Agnese, et al.
Publicado: (2021)

Molecular and Functional Phenotypes of Human Bone Marrow-Derived Mesenchymal Stromal Cells Depend on Harvesting Techniques
por: Walter, Sebastian G., et al.
Publicado: (2020)

Phenotypic and Functional Characterizations of Mesenchymal Stem/Stromal Cells Isolated From Human Cranial Bone Marrow
por: Yang, Kaichuang, et al.
Publicado: (2022)

Utilisation of Quartz Crystal Microbalance Sensors with Dissipation (QCM-D) for a Clauss Fibrinogen Assay in Comparison with Common Coagulation Reference Methods
por: Oberfrank, Stephanie, et al.
Publicado: (2016)

Osteoblastic differentiation of bone marrow mesenchymal stromal cells in Bruck Syndrome
por: Kaneto, Carla M., et al.
Publicado: (2016)

Bone marrow-derived mesenchymal stromal cells differ in their attachment to fibronectin-derived peptides from term placenta-derived mesenchymal stromal cells
por: Maerz, Jan K., et al.
Publicado: (2016)

Wound Fluid from Breast Cancer Patients Undergoing Intraoperative Radiotherapy Exhibits an Altered Cytokine Profile and Impairs Mesenchymal Stromal Cell Function
por: Wuhrer, Anne, et al.
Publicado: (2021)

Mesenchymal stromal cells from bone marrow treated with bovine tendon extract acquire the phenotype of mature tenocytes()
por: Augusto, Lívia Maria Mendonça, et al.
Publicado: (2016)

A robust potency assay highlights significant donor variation of human mesenchymal stem/progenitor cell immune modulatory capacity and extended radio-resistance
por: Ketterl, Nina, et al.
Publicado: (2015)

A Mesenchymal Stromal Cell Gene Signature for Donor Age
por: Alves, Hugo, et al.
Publicado: (2012)

Bone marrow-derived mesenchymal stromal cell: what next?
por: Borges, Fernanda T, et al.
Publicado: (2018)

Bone Marrow Mesenchymal Stromal Cells: Identification, Classification, and Differentiation
por: Gao, Qianmin, et al.
Publicado: (2022)

Cellular Heterogeneity of Mesenchymal Stem/Stromal Cells in the Bone Marrow
por: Mabuchi, Yo, et al.
Publicado: (2021)

Editorial: Differentiation and Regulation of Bone Marrow Mesenchymal Stromal Cells
por: Zhang, Hao, et al.
Publicado: (2022)

Bioreactor for mobilization of mesenchymal stem/stromal cells into scaffolds under mechanical stimulation: Preliminary results
por: Gamez, Carolina, et al.
Publicado: (2020)

Characterization of freshly isolated bone marrow mesenchymal stromal cells from healthy donors and patients with multiple myeloma: transcriptional modulation of the microenvironment
por: Alameda, Daniel, et al.
Publicado: (2020)

Donor age effects on in vitro chondrogenic and osteogenic differentiation performance of equine bone marrow- and adipose tissue-derived mesenchymal stromal cells
por: Bagge, Jasmin, et al.
Publicado: (2022)

Multi-Parameter Analysis of Biobanked Human Bone Marrow Stromal Cells Shows Little Influence for Donor Age and Mild Comorbidities on Phenotypic and Functional Properties
por: Andrzejewska, Anastazja, et al.
Publicado: (2019)

Hypoxic Preconditioning Increases Survival and Pro-Angiogenic Capacity of Human Cord Blood Mesenchymal Stromal Cells In Vitro
por: Bader, Andreas Matthäus, et al.
Publicado: (2015)

Arrhythmogenic Cardiomyopathy Is a Multicellular Disease Affecting Cardiac and Bone Marrow Mesenchymal Stromal Cells
por: Scalco, Arianna, et al.
Publicado: (2021)

Batch Effects during Human Bone Marrow Stromal Cell Propagation Prevail Donor Variation and Culture Duration: Impact on Genotype, Phenotype and Function
por: Brachtl, Gabriele, et al.
Publicado: (2022)

Superparamagnetic Iron Oxide Nanoparticles Labeling of Bone Marrow Stromal (Mesenchymal) Cells Does Not Affect Their “Stemness”
por: Balakumaran, Arun, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_enm1h90517h81l7u49mk2rh5e3