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Inference of synergy/antagonism between anticancer drugs from the pooled analysis of clinical trials

BACKGROUND: Drug interactions can have a significant impact on the response to combinatorial therapy for anticancer treatment. In some instances these interactions can be anticipated based on pre-clinical models. However, the anticipation of drug interactions in the clinical context is in general a...

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Detalles Bibliográficos
Autores principales: Kang, Wenfeng, DiPaola, Robert S, Vazquez, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694030/
https://www.ncbi.nlm.nih.gov/pubmed/23758906
http://dx.doi.org/10.1186/1471-2288-13-77