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Drop drying on surfaces determines chemical reactivity - the specific case of immobilization of oligonucleotides on microarrays

BACKGROUND: Drop drying is a key factor in a wide range of technical applications, including spotted microarrays. The applied nL liquid volume provides specific reaction conditions for the immobilization of probe molecules to a chemically modified surface. RESULTS: We investigated the influence of n...

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Detalles Bibliográficos
Autores principales: Sobek, Jens, Aquino, Catharine, Weigel, Wilfried, Schlapbach, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694035/
https://www.ncbi.nlm.nih.gov/pubmed/23758982
http://dx.doi.org/10.1186/2046-1682-6-8