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Association between an Alzheimer’s Disease-Related Index and APOE ε4 Gene Dose

BACKGROUND: We introduced a hypometabolic convergence index (HCI) to characterize in a single measurement the extent to which a person’s fluorodeoxyglucose positron emission tomogram (FDG PET) corresponds to that in Alzheimer’s disease (AD). Apolipoprotein E ε4 (APOE ε4) gene dose is associated with...

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Detalles Bibliográficos
Autores principales: Schraml, Frank, Chen, Kewei, Ayutyanont, Napatkamon, Auttawut, Roontiva, Langbaum, Jessica B. S., Lee, Wendy, Liu, Xiaofen, Bandy, Dan, Reeder, Stephanie Q., Alexander, Gene E., Caselli, Richard J., Fleisher, Adam S., Reiman, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694066/
https://www.ncbi.nlm.nih.gov/pubmed/23840615
http://dx.doi.org/10.1371/journal.pone.0067163