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Association between an Alzheimer’s Disease-Related Index and APOE ε4 Gene Dose
BACKGROUND: We introduced a hypometabolic convergence index (HCI) to characterize in a single measurement the extent to which a person’s fluorodeoxyglucose positron emission tomogram (FDG PET) corresponds to that in Alzheimer’s disease (AD). Apolipoprotein E ε4 (APOE ε4) gene dose is associated with...
Autores principales: | Schraml, Frank, Chen, Kewei, Ayutyanont, Napatkamon, Auttawut, Roontiva, Langbaum, Jessica B. S., Lee, Wendy, Liu, Xiaofen, Bandy, Dan, Reeder, Stephanie Q., Alexander, Gene E., Caselli, Richard J., Fleisher, Adam S., Reiman, Eric M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694066/ https://www.ncbi.nlm.nih.gov/pubmed/23840615 http://dx.doi.org/10.1371/journal.pone.0067163 |
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