Cargando…
Stochastic Tunneling of Two Mutations in a Population of Cancer Cells
Cancer initiation, progression, and the emergence of drug resistance are driven by specific genetic and/or epigenetic alterations such as point mutations, structural alterations, DNA methylation and histone modification changes. These alterations may confer advantageous, deleterious or neutral effec...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694076/ https://www.ncbi.nlm.nih.gov/pubmed/23840359 http://dx.doi.org/10.1371/journal.pone.0065724 |