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Novel MicroRNA Reporter Uncovers Repression of Let-7 by GSK-3β
Several members of the let-7 microRNA family are downregulated in ovarian and other cancers. They are thought to act as tumor suppressors by lowering growth-promoting and anti-apoptotic proteins. In order to measure cellular let-7 levels systematically, we have developed a highly sensitive let-7 rep...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694080/ https://www.ncbi.nlm.nih.gov/pubmed/23840442 http://dx.doi.org/10.1371/journal.pone.0066330 |