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Neutrophils Turn Plasma Proteins into Weapons against HIV-1

As a consequence of innate immune activation granulocytes and macrophages produce hypochlorite/hypochlorous acid (HOCl) via secretion of myeloperoxidase (MPO) to the outside of the cells, where HOCl immediately reacts with proteins. Most proteins that become altered by this system do not belong to t...

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Detalles Bibliográficos
Autores principales: Speth, Cornelia, Brodde, Martin F., Hagleitner, Magdalena, Rambach, Günter, Van Aken, Hugo, Dierich, Manfred, Kehrel, Beate E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694086/
https://www.ncbi.nlm.nih.gov/pubmed/23840401
http://dx.doi.org/10.1371/journal.pone.0066073