Design of High-Specificity Nanocarriers by Exploiting Non-Equilibrium Effects in Cancer Cell Targeting

Although targeting of cancer cells using drug-delivering nanocarriers holds promise for improving therapeutic agent specificity, the strategy of maximizing ligand affinity for receptors overexpressed on cancer cells is suboptimal. To determine design principles that maximize nanocarrier specificity...

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Detalles Bibliográficos
Autores principales: Tsekouras, Konstantinos, Goncharenko, Igor, Colvin, Michael E., Huang, Kerwyn Casey, Gopinathan, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694107/
https://www.ncbi.nlm.nih.gov/pubmed/23840346
http://dx.doi.org/10.1371/journal.pone.0065623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694107/
https://www.ncbi.nlm.nih.gov/pubmed/23840346
http://dx.doi.org/10.1371/journal.pone.0065623

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