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Design of High-Specificity Nanocarriers by Exploiting Non-Equilibrium Effects in Cancer Cell Targeting
Although targeting of cancer cells using drug-delivering nanocarriers holds promise for improving therapeutic agent specificity, the strategy of maximizing ligand affinity for receptors overexpressed on cancer cells is suboptimal. To determine design principles that maximize nanocarrier specificity...
Autores principales: | Tsekouras, Konstantinos, Goncharenko, Igor, Colvin, Michael E., Huang, Kerwyn Casey, Gopinathan, Ajay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694107/ https://www.ncbi.nlm.nih.gov/pubmed/23840346 http://dx.doi.org/10.1371/journal.pone.0065623 |
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