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Predicting Drug-Target Interactions for New Drug Compounds Using a Weighted Nearest Neighbor Profile

In silico discovery of interactions between drug compounds and target proteins is of core importance for improving the efficiency of the laborious and costly experimental determination of drug-target interaction. Drug-target interaction data are available for many classes of pharmaceutically useful...

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Detalles Bibliográficos
Autores principales: van Laarhoven, Twan, Marchiori, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694117/
https://www.ncbi.nlm.nih.gov/pubmed/23840562
http://dx.doi.org/10.1371/journal.pone.0066952