Impaired expression of protein phosphatase 2A subunits enhances metastatic potential of human prostate cancer cells through activation of AKT pathway

BACKGROUND: Protein phosphatase 2A (PP2A) is a dephosphorylating enzyme, loss of which can contribute to prostate cancer (PCa) pathogenesis. The aim of this study was to analyse the transcriptional and translational expression patterns of individual subunits of the PP2A holoenzyme during PCa progres...

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Detalles Bibliográficos
Autores principales: Pandey, P, Seshacharyulu, P, Das, S, Rachagani, S, Ponnusamy, M P, Yan, Y, Johansson, S L, Datta, K, Fong Lin, M, Batra, S K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694226/
https://www.ncbi.nlm.nih.gov/pubmed/23598299
http://dx.doi.org/10.1038/bjc.2013.160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694226/
https://www.ncbi.nlm.nih.gov/pubmed/23598299
http://dx.doi.org/10.1038/bjc.2013.160

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