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Impaired expression of protein phosphatase 2A subunits enhances metastatic potential of human prostate cancer cells through activation of AKT pathway
BACKGROUND: Protein phosphatase 2A (PP2A) is a dephosphorylating enzyme, loss of which can contribute to prostate cancer (PCa) pathogenesis. The aim of this study was to analyse the transcriptional and translational expression patterns of individual subunits of the PP2A holoenzyme during PCa progres...
Autores principales: | Pandey, P, Seshacharyulu, P, Das, S, Rachagani, S, Ponnusamy, M P, Yan, Y, Johansson, S L, Datta, K, Fong Lin, M, Batra, S K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694226/ https://www.ncbi.nlm.nih.gov/pubmed/23598299 http://dx.doi.org/10.1038/bjc.2013.160 |
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