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A phase II study of weekly neoadjuvant chemotherapy followed by radical chemoradiation for locally advanced cervical cancer

BACKGROUND: We investigated the feasibility of dose-dense neoadjuvant chemotherapy (NACT) with paclitaxel and carboplatin before radical chemoradiation (CRT) and assessed the response rate to such a regimen. METHODS: CxII is a single-arm phase II trial of 46 patients, with locally advanced cervical...

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Detalles Bibliográficos
Autores principales: McCormack, M, Kadalayil, L, Hackshaw, A, Hall-Craggs, M A, Symonds, R P, Warwick, V, Simonds, H, Fernando, I, Hammond, M, James, L, Feeney, A, Ledermann, J A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694233/
https://www.ncbi.nlm.nih.gov/pubmed/23695016
http://dx.doi.org/10.1038/bjc.2013.230