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Somatostatin Receptor 1, a novel EBV-associated CpG hypermethylated gene, contributes to the pathogenesis of EBV-associated gastric cancer

BACKGROUND: Somatostatin receptor 1 (SSTR1) was preferentially methylated in Epstein-Barr virus (EBV)-positive gastric cancer using promoter methylation array. We aimed to analyse the epigenetic alteration and biological function of SSTR1 in EBV-associated gastric cancer (EBVaGC). METHODS: Promoter...

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Detalles Bibliográficos
Autores principales: Zhao, J, Liang, Q, Cheung, K-F, Kang, W, Dong, Y, Lung, R W-M, Tong, J H-M, To, K-F, Sung, J J Y, Yu, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694244/
https://www.ncbi.nlm.nih.gov/pubmed/23722468
http://dx.doi.org/10.1038/bjc.2013.263