p28, A first in class peptide inhibitor of cop1 binding to p53

BACKGROUND: A 28 amino-acid (aa) cell-penetrating peptide (p28) derived from azurin, a redox protein secreted from the opportunistic pathogen Pseudomonas aeruginosa, produces a post-translational increase in p53 in cancer cells by inhibiting its ubiquitination. METHODS: In silico computational simul...

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Detalles Bibliográficos
Autores principales: Yamada, T, Christov, K, Shilkaitis, A, Bratescu, L, Green, A, Santini, S, Bizzarri, A R, Cannistraro, S, Gupta, T K D, Beattie, C W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694247/
https://www.ncbi.nlm.nih.gov/pubmed/23736031
http://dx.doi.org/10.1038/bjc.2013.266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694247/
https://www.ncbi.nlm.nih.gov/pubmed/23736031
http://dx.doi.org/10.1038/bjc.2013.266

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