Establishment of a simplified in vitro porcine blood–brain barrier model with high transendothelial electrical resistance

Good in vitro blood–brain barrier (BBB) models that mimic the in vivo BBB phenotype are essential for studies on BBB functionality and for initial screening in drug discovery programmes, as many potential therapeutic drug candidates have poor BBB permeation. Difficulties associated with the availabi...

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Detalles Bibliográficos
Autores principales: Patabendige, Adjanie, Skinner, Robert A., Abbott, N. Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2013
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694297/
https://www.ncbi.nlm.nih.gov/pubmed/22789905
http://dx.doi.org/10.1016/j.brainres.2012.06.057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694297/
https://www.ncbi.nlm.nih.gov/pubmed/22789905
http://dx.doi.org/10.1016/j.brainres.2012.06.057

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