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The effect of peptide adsorption on signal linearity and a simple approach to improve reliability of quantification()

Peptide quantification using MS often relies on the comparison of peptide signal intensities between different samples, which is based on the assumption that observed signal intensity has a linear relationship to peptide abundance. A typical proteomics experiment is subject to multiple sources of va...

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Detalles Bibliográficos
Autores principales: Warwood, Stacey, Byron, Adam, Humphries, Martin J., Knight, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694305/
https://www.ncbi.nlm.nih.gov/pubmed/23665148
http://dx.doi.org/10.1016/j.jprot.2013.04.034