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Modelling the endothelial blood-CNS barriers: a method for the production of robust in vitro models of the rat blood-brain barrier and blood-spinal cord barrier

BACKGROUND: Modelling the blood-CNS barriers of the brain and spinal cord in vitro continues to provide a considerable challenge for research studying the passage of large and small molecules in and out of the central nervous system, both within the context of basic biology and for pharmaceutical dr...

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Detalles Bibliográficos
Autores principales: Watson, P Marc D, Paterson, Judy C, Thom, George, Ginman, Ulrika, Lundquist, Stefan, Webster, Carl I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694476/
https://www.ncbi.nlm.nih.gov/pubmed/23773766
http://dx.doi.org/10.1186/1471-2202-14-59