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Nitric Oxide Is a Mediator of Antiproliferative Effects Induced by Proinflammatory Cytokines on Pancreatic Beta Cells

Nitric oxide (NO) is involved in several biological processes. In type 1 diabetes mellitus (T1DM), proinflammatory cytokines activate an inducible isoform of NOS (iNOS) in β cells, thus increasing NO levels and inducing apoptosis. The aim of the current study is to determine the role of NO (1) in th...

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Detalles Bibliográficos
Autores principales: Quintana-Lopez, Laura, Blandino-Rosano, Manuel, Perez-Arana, Gonzalo, Cebada-Aleu, Alberto, Lechuga-Sancho, Alfonso, Aguilar-Diosdado, Manuel, Segundo, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694487/
https://www.ncbi.nlm.nih.gov/pubmed/23840099
http://dx.doi.org/10.1155/2013/905175