Cargando…

Role of SIRT3 in the regulation of redox balance during oral carcinogenesis

BACKGROUND: Sirtuins (SIRT1-7) are a family of NAD-dependent deacetylases, which play an important role in regulating cancer tumorigenesis; however, their role in oral cancer has been controversial. SIRT3 is localized in the mitochondria, where it deacetylates and activates several enzymes involved...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, I-Chieh, Chiang, Wei-Fan, Liu, Shyun-Yeu, Chen, Pei-Fen, Chiang, Hung-Che
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694519/
https://www.ncbi.nlm.nih.gov/pubmed/23800187
http://dx.doi.org/10.1186/1476-4598-12-68