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Tandutinib (MLN518) reverses multidrug resistance by inhibiting the efflux activity of the multidrug resistance protein 7 (ABCC10)

It is well established that ATP-binding cassette (ABC) transporter-mediated multidrug resistance (MDR) is one of the major mechanisms that causes resistance to antineoplastic drugs in cancer cells. ABC transporters can significantly decrease the intracellular concentration of antineoplastic drugs by...

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Detalles Bibliográficos
Autores principales: DENG, WEN, DAI, CHUN-LING, CHEN, JUN-JIANG, KATHAWALA, RISHIL J., SUN, YUE-LI, CHEN, HAI-FAN, FU, LI-WU, CHEN, ZHE-SHENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694559/
https://www.ncbi.nlm.nih.gov/pubmed/23525656
http://dx.doi.org/10.3892/or.2013.2362