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Bmal1 suppresses cancer cell invasion by blocking the phosphoinositide 3-kinase-Akt-MMP-2 signaling pathway

Bmal1 is a core factor in the regulation of circadian rhythms. Previous studies have shown that Bmal1 suppresses tumor growth in cell culture and animal models and is down-regulated in certain types of cancer. The aim of the present study was to investigated whether Bmal1 influences the invasiveness...

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Detalles Bibliográficos
Autores principales: JUNG, CHAN-HUN, KIM, EUN MI, PARK, JONG KUK, HWANG, SANG-GU, MOON, SUNG-KWON, KIM, WUN-JAE, UM, HONG-DUCK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694561/
https://www.ncbi.nlm.nih.gov/pubmed/23563360
http://dx.doi.org/10.3892/or.2013.2381