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Bmal1 suppresses cancer cell invasion by blocking the phosphoinositide 3-kinase-Akt-MMP-2 signaling pathway
Bmal1 is a core factor in the regulation of circadian rhythms. Previous studies have shown that Bmal1 suppresses tumor growth in cell culture and animal models and is down-regulated in certain types of cancer. The aim of the present study was to investigated whether Bmal1 influences the invasiveness...
Autores principales: | JUNG, CHAN-HUN, KIM, EUN MI, PARK, JONG KUK, HWANG, SANG-GU, MOON, SUNG-KWON, KIM, WUN-JAE, UM, HONG-DUCK |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694561/ https://www.ncbi.nlm.nih.gov/pubmed/23563360 http://dx.doi.org/10.3892/or.2013.2381 |
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