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Haplotype assembly in polyploid genomes and identical by descent shared tracts

Motivation: Genome-wide haplotype reconstruction from sequence data, or haplotype assembly, is at the center of major challenges in molecular biology and life sciences. For complex eukaryotic organisms like humans, the genome is vast and the population samples are growing so rapidly that algorithms...

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Detalles Bibliográficos
Autores principales: Aguiar, Derek, Istrail, Sorin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694639/
https://www.ncbi.nlm.nih.gov/pubmed/23813004
http://dx.doi.org/10.1093/bioinformatics/btt213