Stability selection for regression-based models of transcription factor–DNA binding specificity

Motivation: The DNA binding specificity of a transcription factor (TF) is typically represented using a position weight matrix model, which implicitly assumes that individual bases in a TF binding site contribute independently to the binding affinity, an assumption that does not always hold. For thi...

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Detalles Bibliográficos
Autores principales: Mordelet, Fantine, Horton, John, Hartemink, Alexander J., Engelhardt, Barbara E., Gordân, Raluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Ismb/Eccb 2013 Proceedings Papers Committee July 21 to July 23, 2013, Berlin, Germany
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694650/
https://www.ncbi.nlm.nih.gov/pubmed/23812975
http://dx.doi.org/10.1093/bioinformatics/btt221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694650/
https://www.ncbi.nlm.nih.gov/pubmed/23812975
http://dx.doi.org/10.1093/bioinformatics/btt221

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