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Poly(A) motif prediction using spectral latent features from human DNA sequences

Motivation: Polyadenylation is the addition of a poly(A) tail to an RNA molecule. Identifying DNA sequence motifs that signal the addition of poly(A) tails is essential to improved genome annotation and better understanding of the regulatory mechanisms and stability of mRNA. Existing poly(A) motif p...

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Detalles Bibliográficos
Autores principales: Xie, Bo, Jankovic, Boris R., Bajic, Vladimir B., Song, Le, Gao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694652/
https://www.ncbi.nlm.nih.gov/pubmed/23813000
http://dx.doi.org/10.1093/bioinformatics/btt218