A weighted sampling algorithm for the design of RNA sequences with targeted secondary structure and nucleotide distribution

Motivations: The design of RNA sequences folding into predefined secondary structures is a milestone for many synthetic biology and gene therapy studies. Most of the current software uses similar local search strategies (i.e. a random seed is progressively adapted to acquire the desired folding prop...

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Detalles Bibliográficos
Autores principales: Reinharz, Vladimir, Ponty, Yann, Waldispühl, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Ismb/Eccb 2013 Proceedings Papers Committee July 21 to July 23, 2013, Berlin, Germany
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694657/
https://www.ncbi.nlm.nih.gov/pubmed/23812999
http://dx.doi.org/10.1093/bioinformatics/btt217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694657/
https://www.ncbi.nlm.nih.gov/pubmed/23812999
http://dx.doi.org/10.1093/bioinformatics/btt217

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