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A weighted sampling algorithm for the design of RNA sequences with targeted secondary structure and nucleotide distribution
Motivations: The design of RNA sequences folding into predefined secondary structures is a milestone for many synthetic biology and gene therapy studies. Most of the current software uses similar local search strategies (i.e. a random seed is progressively adapted to acquire the desired folding prop...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694657/ https://www.ncbi.nlm.nih.gov/pubmed/23812999 http://dx.doi.org/10.1093/bioinformatics/btt217 |