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Predicting protein contact map using evolutionary and physical constraints by integer programming

Motivation: Protein contact map describes the pairwise spatial and functional relationship of residues in a protein and contains key information for protein 3D structure prediction. Although studied extensively, it remains challenging to predict contact map using only sequence information. Most exis...

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Detalles Bibliográficos
Autores principales: Wang, Zhiyong, Xu, Jinbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694661/
https://www.ncbi.nlm.nih.gov/pubmed/23812992
http://dx.doi.org/10.1093/bioinformatics/btt211