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Simple topological properties predict functional misannotations in a metabolic network

Motivation: Misannotation in sequence databases is an important obstacle for automated tools for gene function annotation, which rely extensively on comparison with sequences with known function. To improve current annotations and prevent future propagation of errors, sequence-independent tools are,...

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Detalles Bibliográficos
Autores principales: Liberal, Rodrigo, Pinney, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694667/
https://www.ncbi.nlm.nih.gov/pubmed/23812979
http://dx.doi.org/10.1093/bioinformatics/btt236