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IDBA-tran: a more robust de novo de Bruijn graph assembler for transcriptomes with uneven expression levels

Motivation: RNA sequencing based on next-generation sequencing technology is effective for analyzing transcriptomes. Like de novo genome assembly, de novo transcriptome assembly does not rely on any reference genome or additional annotation information, but is more difficult. In particular, isoforms...

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Detalles Bibliográficos
Autores principales: Peng, Yu, Leung, Henry C. M., Yiu, Siu-Ming, Lv, Ming-Ju, Zhu, Xin-Guang, Chin, Francis Y. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694675/
https://www.ncbi.nlm.nih.gov/pubmed/23813001
http://dx.doi.org/10.1093/bioinformatics/btt219