Cargando…

Genome-wide identification and predictive modeling of tissue-specific alternative polyadenylation

Motivation: Pre-mRNA cleavage and polyadenylation are essential steps for 3′-end maturation and subsequent stability and degradation of mRNAs. This process is highly controlled by cis-regulatory elements surrounding the cleavage/polyadenylation sites (polyA sites), which are frequently constrained b...

Descripción completa

Detalles Bibliográficos
Autores principales: Hafez, Dina, Ni, Ting, Mukherjee, Sayan, Zhu, Jun, Ohler, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694680/
https://www.ncbi.nlm.nih.gov/pubmed/23812974
http://dx.doi.org/10.1093/bioinformatics/btt233