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Genome-wide identification and predictive modeling of tissue-specific alternative polyadenylation
Motivation: Pre-mRNA cleavage and polyadenylation are essential steps for 3′-end maturation and subsequent stability and degradation of mRNAs. This process is highly controlled by cis-regulatory elements surrounding the cleavage/polyadenylation sites (polyA sites), which are frequently constrained b...
Autores principales: | Hafez, Dina, Ni, Ting, Mukherjee, Sayan, Zhu, Jun, Ohler, Uwe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694680/ https://www.ncbi.nlm.nih.gov/pubmed/23812974 http://dx.doi.org/10.1093/bioinformatics/btt233 |
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