Dual Delayed Feedback Provides Sensitivity and Robustness to the NF-κB Signaling Module

Many cellular stress-responsive signaling systems exhibit highly dynamic behavior with oscillatory features mediated by delayed negative feedback loops. What remains unclear is whether oscillatory behavior is the basis for a signaling code based on frequency modulation (FM) or whether the negative f...

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Detalles Bibliográficos
Autores principales: Longo, Diane M., Selimkhanov, Jangir, Kearns, Jeffrey D., Hasty, Jeff, Hoffmann, Alexander, Tsimring, Lev S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694842/
https://www.ncbi.nlm.nih.gov/pubmed/23825938
http://dx.doi.org/10.1371/journal.pcbi.1003112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694842/
https://www.ncbi.nlm.nih.gov/pubmed/23825938
http://dx.doi.org/10.1371/journal.pcbi.1003112

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