DNA Methylation Restricts Lineage-specific Functions of Transcription Factor Gata4 during Embryonic Stem Cell Differentiation

DNA methylation changes dynamically during development and is essential for embryogenesis in mammals. However, how DNA methylation affects developmental gene expression and cell differentiation remains elusive. During embryogenesis, many key transcription factors are used repeatedly, triggering diff...

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Detalles Bibliográficos
Autores principales: Oda, Masaaki, Kumaki, Yuichi, Shigeta, Masaki, Jakt, Lars Martin, Matsuoka, Chisa, Yamagiwa, Akiko, Niwa, Hitoshi, Okano, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694845/
https://www.ncbi.nlm.nih.gov/pubmed/23825962
http://dx.doi.org/10.1371/journal.pgen.1003574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694845/
https://www.ncbi.nlm.nih.gov/pubmed/23825962
http://dx.doi.org/10.1371/journal.pgen.1003574

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