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Negative Regulation of TLR Inflammatory Signaling by the SUMO-deconjugating Enzyme SENP6

The signaling of Toll-like receptors (TLRs) induces host defense against microbial invasion. Protein posttranslational modifications dynamically shape the strength and duration of the signaling pathways. It is intriguing to explore whether de-SUMOylation could modulate the TLR signaling. Here we ide...

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Detalles Bibliográficos
Autores principales: Liu, Xing, Chen, Wei, Wang, Qiang, Li, Li, Wang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694847/
https://www.ncbi.nlm.nih.gov/pubmed/23825957
http://dx.doi.org/10.1371/journal.ppat.1003480