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Negative Regulation of TLR Inflammatory Signaling by the SUMO-deconjugating Enzyme SENP6
The signaling of Toll-like receptors (TLRs) induces host defense against microbial invasion. Protein posttranslational modifications dynamically shape the strength and duration of the signaling pathways. It is intriguing to explore whether de-SUMOylation could modulate the TLR signaling. Here we ide...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694847/ https://www.ncbi.nlm.nih.gov/pubmed/23825957 http://dx.doi.org/10.1371/journal.ppat.1003480 |